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Iridium(I)-catalyzed α-C(sp(3))–H Alkylation of Saturated Azacycles

Saturated azacycles are commonly encountered in bioactive compounds and approved therapeutic agents. The development of methods for functionalization of the α-methylene C‒H bonds of these highly privileged building blocks is of great importance, especially in drug discovery. While much effort has be...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Autores principales: Verma, Pritha, Richter, Jeremy M., Chekshin, Nikita, Qiao, Jennifer X., Yu, Jin-Quan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7219544/
https://ncbi.nlm.nih.gov/pubmed/32098471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b12320
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