Activation of the NLRP3 inflammasome in lipopolysaccharide-induced mouse fatigue and its relevance to chronic fatigue syndrome

BACKGROUND: The NLRP3 inflammasome (NOD-like receptor family, pyrin domain containing 3) is an intracellular protein complex that plays an important role in innate immune sensing. Its activation leads to the maturation of caspase-1 and regulates the cleavage of interleukin (IL)-1β and IL-18. Various...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Zhang, Zi-Teng, Du, Xiu-Ming, Ma, Xiu-Juan, Zong, Ying, Chen, Ji-Kuai, Yu, Chen-Lin, Liu, Yan-Gang, Chen, Yong-Chun, Zhao, Li-Jun, Lu, Guo-Cai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822300/
https://ncbi.nlm.nih.gov/pubmed/27048470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0539-1
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