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NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages
A limit to the clinical benefit of radiotherapy is not an incapacity to eliminate tumor cells but rather a limit on its capacity to do so without destroying normal tissue and inducing inflammation. Recent evidence reveals that the inflammasome is essential for mediating radiation-induced cell and ti...
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Publicado no: | Cell Death Dis |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5386456/ https://ncbi.nlm.nih.gov/pubmed/28151471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.460 |
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