NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages

A limit to the clinical benefit of radiotherapy is not an incapacity to eliminate tumor cells but rather a limit on its capacity to do so without destroying normal tissue and inducing inflammation. Recent evidence reveals that the inflammasome is essential for mediating radiation-induced cell and ti...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Liu, Yan-gang, Chen, Ji-kuai, Zhang, Zi-teng, Ma, Xiu-juan, Chen, Yong-chun, Du, Xiu-ming, Liu, Hong, Zong, Ying, Lu, Guo-cai
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386456/
https://ncbi.nlm.nih.gov/pubmed/28151471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.460
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