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Fluoxetine Inhibits NLRP3 Inflammasome Activation: Implication in Depression

BACKGROUND: Emerging evidence indicates that NLRP3 inflammasome-induced inflammation plays a crucial role in the pathogenesis of depression. Thus, inhibition of NLRP3 inflammasome activation may offer a therapeutic benefit in the treatment of depression. Fluoxetine, a widely used antidepressant, has...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Du, Ren-Hong, Tan, Jun, Sun, Xi-Yang, Lu, Ming, Ding, Jian-Hua, Hu, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043644/
https://ncbi.nlm.nih.gov/pubmed/27207922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyw037
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