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Cerebrovascular contributions to aging and Alzheimer's disease in Down syndrome
Down syndrome (DS) is a common cause of intellectual disability and is also associated with early age of onset of Alzheimer's disease (AD). Due to an extra copy of chromosome 21, most adults over 40 years old with DS have beta-amyloid plaques as a result of overexpression of the amyloid precurs...
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| Udgivet i: | Biochim Biophys Acta |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821721/ https://ncbi.nlm.nih.gov/pubmed/26593849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.11.007 |
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