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Cerebrovascular contributions to aging and Alzheimer's disease in Down syndrome

Down syndrome (DS) is a common cause of intellectual disability and is also associated with early age of onset of Alzheimer's disease (AD). Due to an extra copy of chromosome 21, most adults over 40 years old with DS have beta-amyloid plaques as a result of overexpression of the amyloid precurs...

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Bibliografische gegevens
Gepubliceerd in:Biochim Biophys Acta
Hoofdauteurs: Wilcock, Donna M., Schmitt, Frederick A., Head, Elizabeth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821721/
https://ncbi.nlm.nih.gov/pubmed/26593849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.11.007
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