Myeloid-derived suppressor cell survival and function are regulated by the transcription factor Nrf2()

Tumor-induced myeloid-derived suppressor cells (MDSC) contribute to immune suppression in tumor-bearing individuals and are a major obstacle to effective immunotherapy. Reactive oxygen species (ROS) are one of the mechanisms used by MDSC to suppress T cell activation. Although ROS are toxic to most...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Beury, Daniel W., Carter, Kayla A., Nelson, Cassandra, Sinha, Pratima, Hanson, Erica, Nyandjo, Maeva, Fitzgerald, Phillip J., Majeed, Amry, Wali, Neha, Ostrand-Rosenberg, Suzanne
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821672/
https://ncbi.nlm.nih.gov/pubmed/26936880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501785
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker