Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4

Myeloid-derived suppressor cells (MDSC) are potent inhibitors of anti-tumor immunity that facilitate tumor progression by blocking the activation of CD4(+) and CD8(+) T cells and by promoting a type 2 immune response through their production of IL-10 and down-regulation of macrophage production of I...

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Bibliographic Details
Main Authors: Bunt, Stephanie K., Clements, Virginia K., Hanson, Erica M., Sinha, Pratima, Ostrand-Rosenberg, Suzanne
Format: Artigo
Language:Inglês
Published: The Society for Leukocyte Biology 2009
Subjects:
Inflammation, Extracellular Mediators, and Effector Molecules
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698586/
https://ncbi.nlm.nih.gov/pubmed/19261929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0708446
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