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Myeloid-Derived Suppressor Cells Down-Regulate L-Selectin Expression on CD4(+) and CD8(+) T Cells

Effective cell-mediated antitumor immunity requires the activation of tumor-reactive T cells and the trafficking of activated T cells to tumor sites. These processes involve the extravasation of lymphocytes from the blood and lymphatics, and their homing to lymph nodes and tumors. L-selectin (CD62L)...

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Autors principals: Hanson, Erica M., Clements, Virginia K., Sinha, Pratima, Ilkovitch, Dan, Ostrand-Rosenberg, Suzanne
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800824/
https://ncbi.nlm.nih.gov/pubmed/19553533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804253
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