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Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs
Recent evidence has strongly implicated IL‐36 cytokines as key initiators of inflammation in the skin barrier. IL‐36 cytokines belong to the extended IL‐1 family and, similar to most members of this family, are expressed as inactive precursors that require proteolytic processing for activation. Beca...
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| Veröffentlicht in: | FEBS Open Bio |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4821354/ https://ncbi.nlm.nih.gov/pubmed/27239446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12044 |
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