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Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs

Recent evidence has strongly implicated IL‐36 cytokines as key initiators of inflammation in the skin barrier. IL‐36 cytokines belong to the extended IL‐1 family and, similar to most members of this family, are expressed as inactive precursors that require proteolytic processing for activation. Beca...

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Detaylı Bibliyografya
Yayımlandı:FEBS Open Bio
Asıl Yazarlar: Clancy, Danielle M., Henry, Conor M., Davidovich, Pavel B., Sullivan, Graeme P., Belotcerkovskaya, Ekaterina, Martin, Seamus J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821354/
https://ncbi.nlm.nih.gov/pubmed/27239446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12044
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