Macrophage Migration Inhibitory Factor: A Novel Inhibitor of Apoptosis Signal-Regulating Kinase 1–p38–Xanthine Oxidoreductase–Dependent Cigarette Smoke–Induced Apoptosis

Cigarette smoke (CS) exposure is the leading cause of emphysema. CS mediates pathologic emphysematous remodeling of the lung via apoptosis of lung parenchymal cells resulting in enlargement of the airspaces, loss of the capillary bed, and diminished surface area for gas exchange. Macrophage migratio...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Fallica, Jonathan, Varela, Lidenys, Johnston, Laura, Kim, Bo, Serebreni, Leonid, Wang, Lan, Damarla, Mahendra, Kolb, Todd M., Hassoun, Paul M., Damico, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821049/
https://ncbi.nlm.nih.gov/pubmed/26390063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0403OC
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