XOR inhibition with febuxostat accelerates pulmonary endothelial barrier recovery and improves survival in lipopolysaccharide‐induced murine sepsis

Sepsis is a leading cause of death among patients in the intensive care unit, resulting from multi‐organ failure. Activity of xanthine oxidoreductase (XOR), a reactive oxygen species (ROS) producing enzyme, is known to be elevated in nonsurvivors of sepsis compared to survivors. We have previously d...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Damarla, Mahendra, Johnston, Laura F., Liu, Gigi, Gao, Li, Wang, Lan, Varela, Lidenys, Kolb, Todd M., Kim, Bo S., Damico, Rachel L., Hassoun, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555900/
https://ncbi.nlm.nih.gov/pubmed/28801519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13377
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados