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p53 Mediates Cigarette Smoke–Induced Apoptosis of Pulmonary Endothelial Cells: Inhibitory Effects of Macrophage Migration Inhibitor Factor

Exposure to cigarette smoke (CS) is the most common cause of emphysema, a debilitating pulmonary disease histopathologically characterized by the irreversible destruction of lung architecture. Mounting evidence links enhanced endothelial apoptosis causally to the development of emphysema. However, t...

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Detalhes bibliográficos
Main Authors: Damico, Rachel, Simms, Tiffany, Kim, Bo S., Tekeste, Zenar, Amankwan, Henry, Damarla, Mahendra, Hassoun, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095933/
https://ncbi.nlm.nih.gov/pubmed/20448056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0379OC
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