TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus

BACKGROUND: Recent genome-wide association studies revealed TREM2 rs75932628-T variant to be associated with Alzheimer’s disease (AD) and other neurodegenerative diseases. However, the role that TREM2 plays in sporadic AD is largely unknown. Our aim was to assess messenger RNA (mRNA) expression leve...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Celarain, Naiara, Sánchez-Ruiz de Gordoa, Javier, Zelaya, María Victoria, Roldán, Miren, Larumbe, Rosa, Pulido, Laura, Echavarri, Carmen, Mendioroz, Maite
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820985/
https://ncbi.nlm.nih.gov/pubmed/27051467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0202-9
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi