Hippocampal LMNA Gene Expression is Increased in Late-Stage Alzheimer’s Disease

Lamins are fibrillary proteins that are crucial in maintaining nuclear shape and function. Recently, B-type lamin dysfunction has been linked to tauopathies. However, the role of A-type lamin in neurodegeneration is still obscure. Here, we examined A-type and B-type lamin expression levels by RT-qPC...

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Udgivet i:Int J Mol Sci
Main Authors: Méndez-López, Iván, Blanco-Luquin, Idoia, Sánchez-Ruiz de Gordoa, Javier, Urdánoz-Casado, Amaya, Roldán, Miren, Acha, Blanca, Echavarri, Carmen, Zelaya, Victoria, Jericó, Ivonne, Mendioroz, Maite
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413092/
https://ncbi.nlm.nih.gov/pubmed/30781626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040878
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