TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus

BACKGROUND: Recent genome-wide association studies revealed TREM2 rs75932628-T variant to be associated with Alzheimer’s disease (AD) and other neurodegenerative diseases. However, the role that TREM2 plays in sporadic AD is largely unknown. Our aim was to assess messenger RNA (mRNA) expression leve...

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Bibliografiske detaljer
Udgivet i:Clin Epigenetics
Main Authors: Celarain, Naiara, Sánchez-Ruiz de Gordoa, Javier, Zelaya, María Victoria, Roldán, Miren, Larumbe, Rosa, Pulido, Laura, Echavarri, Carmen, Mendioroz, Maite
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820985/
https://ncbi.nlm.nih.gov/pubmed/27051467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0202-9
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