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Ultrasound-promoted two-step synthesis of 3-arylselenylindoles and 3-arylthioindoles as novel combretastatin A-4 analogues

A series of 3-(3′-hydroxy-4′-methoxyphenyl)selenyl-5,6,7-trimethoxy-1H-indoles and 3-(3′-hydroxy-4′-methoxyphenyl)thio-5,6,7-trimethoxy-1H-indoles were obtained as a new class of combretastatin A-4 (CA-4) analogues via a convenient ultrasound (US)-assisted two-step process involving 3-selenenylation...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wen, Zhiyong, Li, Xiaona, Zuo, Daiying, Lang, Binyue, Wu, Yang, Jiang, Mingyang, Ma, Huizhuo, Bao, Kai, Wu, Yingliang, Zhang, Weige
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820744/
https://ncbi.nlm.nih.gov/pubmed/27045272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23986
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