Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation.

The role of insulin-induced receptor autophosphorylation in its internalization was analyzed by comparing 125I-labeled insulin (125I-insulin) internalization in Chinese hamster ovary (CHO) cell lines transfected with normal (CHO.T) or mutated insulin receptors. In four cell lines with a defect of in...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Carpentier, J L, Paccaud, J P, Gorden, P, Rutter, W J, Orci, L
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1729685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.1.162
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