Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation.
The role of insulin-induced receptor autophosphorylation in its internalization was analyzed by comparing 125I-labeled insulin (125I-insulin) internalization in Chinese hamster ovary (CHO) cell lines transfected with normal (CHO.T) or mutated insulin receptors. In four cell lines with a defect of in...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1729685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.1.162 |
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