Receptor-mediated endocytosis of insulin: role of microvilli, coated pits, and coated vesicles.

When 125I-labeled insulin (125I-insulin) is incubated with 3T3-L1 adipocytes and cells processed for electron microscopic autoradiography, the ligand initially localizes preferentially to microvilli and coated pits. As a function of time and temperature, this initial preferential localization to mic...

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Hlavní autoři: Fan, J Y, Carpentier, J L, Gorden, P, Van Obberghen, E, Blackett, N M, Grunfeld, C, Orci, L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1982
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC347433/
https://ncbi.nlm.nih.gov/pubmed/6818548
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