Receptor-mediated endocytosis of insulin: role of microvilli, coated pits, and coated vesicles.

When 125I-labeled insulin (125I-insulin) is incubated with 3T3-L1 adipocytes and cells processed for electron microscopic autoradiography, the ligand initially localizes preferentially to microvilli and coated pits. As a function of time and temperature, this initial preferential localization to mic...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Fan, J Y, Carpentier, J L, Gorden, P, Van Obberghen, E, Blackett, N M, Grunfeld, C, Orci, L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1982
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6818548/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.24.7788
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