The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis

Expression of the initiator methionine tRNA (tRNA(i)(Met)) is deregulated in cancer. Despite this fact, it is not currently known how tRNA(i)(Met) expression levels influence tumor progression. We have found that tRNA(i)(Met) expression is increased in carcinoma-associated fibroblasts, implicating d...

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Detaylı Bibliyografya
Yayımlandı:Curr Biol
Asıl Yazarlar: Clarke, Cassie J., Berg, Tracy J., Birch, Joanna, Ennis, Darren, Mitchell, Louise, Cloix, Catherine, Campbell, Andrew, Sumpton, David, Nixon, Colin, Campbell, Kirsteen, Bridgeman, Victoria L., Vermeulen, Peter B., Foo, Shane, Kostaras, Eleftherios, Jones, J. Louise, Haywood, Linda, Pulleine, Ellie, Yin, Huabing, Strathdee, Douglas, Sansom, Owen, Blyth, Karen, McNeish, Iain, Zanivan, Sara, Reynolds, Andrew R., Norman, Jim C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819511/
https://ncbi.nlm.nih.gov/pubmed/26948875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.01.045
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