The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma

The cell's repertoire of transfer RNAs (tRNAs) has been linked to cancer. Recently, the level of the initiator methionine tRNA (tRNA(i)(Met)) in stromal fibroblasts has been shown to influence extracellular matrix (ECM) secretion to drive tumour growth and angiogenesis. Here we show that increa...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Birch, Joanna, Clarke, Cassie J., Campbell, Andrew D., Campbell, Kirsteen, Mitchell, Louise, Liko, Dritan, Kalna, Gabriela, Strathdee, Douglas, Sansom, Owen J., Neilson, Matthew, Blyth, Karen, Norman, Jim C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087684/
https://ncbi.nlm.nih.gov/pubmed/27543055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.019075
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