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Adult response to olanzapine or clozapine treatment is altered by adolescent antipsychotic exposure: A preclinical test in the phencyclidine hyperlocomotion model

This study examined how repeated olanzapine (OLZ) or clozapine (CLZ) treatment in adolescence alters sensitivity to the same drug in adulthood in the phencyclidine (PCP) hyperlocomotion model. Male adolescent Sprague-Dawley rats (postnatal day (P) 44–48) were first treated with OLZ (1.0 or 2.0 mg/kg...

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Bibliografiska uppgifter
I publikationen:J Psychopharmacol
Huvudupphovsmän: Shu, Qing, Hu, Gang, Li, Ming
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818982/
https://ncbi.nlm.nih.gov/pubmed/24257809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881113512039
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