Iptakalim Preferentially Decreases Nicotine-induced Hyperlocomotion in Phencyclidine-sensitized Rats: A Potential Dual Action against Nicotine Addiction and Psychosis

OBJECTIVE: Iptakalim is a putative ATP-sensitive potassium (K(ATP)) channel opener. It is also a novel nicotinic acetylcholine receptor (nAChR) blocker and can antagonize nicotine-induced increase in dopamine release in the nucleus accumbens. Our recent work also shows that iptakalim exhibits a cloz...

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Sonraí Bibleagrafaíochta
Main Authors: Volf, Nick, Hu, Gang, Li, Ming
Formáid: Artigo
Teanga:Inglês
Foilsithe: Korean College of Neuropsychopharmacology 2012
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569163/
https://ncbi.nlm.nih.gov/pubmed/23430396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9758/cpn.2012.10.3.168
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