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Neural basis of the potentiated inhibition of repeated haloperidol and clozapine treatment on the phencyclidine-induced hyperlocomotion

Clinical observations suggest that antipsychotic effect starts early and increases progressively over time. This time course of antipsychotic effect can be captured in a rat phencyclidine (PCP)-induced hyperlocomotion model, as repeated antipsychotic treatment progressively increases its inhibition...

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Hlavní autoři: Zhao, Changjiu, Sun, Tao, Li, Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389158/
https://ncbi.nlm.nih.gov/pubmed/22476004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2012.03.007
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