SELECTIVE POTENTIATION OF THE METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 2 BLOCKS PHENCYCLIDINE-INDUCED HYPERLOCOMOTION AND BRAIN ACTIVATION

Previous preclinical and clinical studies have demonstrated the efficacy of group II metabotropic glutamate receptor (mGluR) agonists as potential antipsychotics. Recent studies utilizing mGluR2-, mGluR3-, and double knockout mice support that the antipsychotic effects of those compounds are mediate...

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Autors principals: HACKLER, E. A., BYUN, N. E., JONES, C. K., WILLIAMS, J. M., BAHEZA, R., SENGUPTA, S., GRIER, M. D., AVISON, M., CONN, P. J., GORE, J. C.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598608/
https://ncbi.nlm.nih.gov/pubmed/20350588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.02.057
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