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Adult response to olanzapine or clozapine treatment is altered by adolescent antipsychotic exposure: A preclinical test in the phencyclidine hyperlocomotion model

This study examined how repeated olanzapine (OLZ) or clozapine (CLZ) treatment in adolescence alters sensitivity to the same drug in adulthood in the phencyclidine (PCP) hyperlocomotion model. Male adolescent Sprague-Dawley rats (postnatal day (P) 44–48) were first treated with OLZ (1.0 or 2.0 mg/kg...

詳細記述

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書誌詳細
出版年:J Psychopharmacol
主要な著者: Shu, Qing, Hu, Gang, Li, Ming
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818982/
https://ncbi.nlm.nih.gov/pubmed/24257809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881113512039
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