A Feed-Forward Circuit of Endogenous PGC-1α and Estrogen Related Receptor α Regulates the Neuronal Electron Transport Chain

Peroxisome proliferator-activated receptor  γ coactivator 1α (PGC-1α) is a central regulator of cellular and mitochondrial metabolism. Cellular bioenergetics are critically important in “energy-guzzling” neurons, but the components and wiring of the transcriptional circuit through which PGC-1α regul...

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Vydáno v:Parkinsons Dis
Hlavní autoři: Bakshi, Rachit, Mittal, Shuchi, Liao, Zhixiang, Scherzer, Clemens R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818948/
https://ncbi.nlm.nih.gov/pubmed/27088034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2405176
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