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An IκB Kinase-regulated feed-forward circuit prolongs inflammation

Loss of NF-κB signaling causes immunodeficiency while inhibition of NF-κB can be efficacious in treating chronic inflammatory disease. Inflammatory NF-κB signaling must therefore be tightly regulated, and while many mechanisms to downregulate NF-κB have been elucidated, there have only been limited...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Perez, Jessica M., Chirieleison, Steven M., Abbott, Derek W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520735/
https://ncbi.nlm.nih.gov/pubmed/26190110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.050
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