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An IκB Kinase-regulated feed-forward circuit prolongs inflammation
Loss of NF-κB signaling causes immunodeficiency while inhibition of NF-κB can be efficacious in treating chronic inflammatory disease. Inflammatory NF-κB signaling must therefore be tightly regulated, and while many mechanisms to downregulate NF-κB have been elucidated, there have only been limited...
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| Pubblicato in: | Cell Rep |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4520735/ https://ncbi.nlm.nih.gov/pubmed/26190110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.050 |
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