Mutation Detection in an Antibody-Producing Chinese Hamster Ovary Cell Line by Targeted RNA Sequencing

Chinese hamster ovary (CHO) cells have been used widely in the pharmaceutical industry for production of biological therapeutics including monoclonal antibodies (mAb). The integrity of the gene of interest and the accuracy of the relay of genetic information impact product quality and patient safety...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Zhang, Siyan, Hughes, Jason D., Murgolo, Nicholas, Levitan, Diane, Chen, Janice, Liu, Zhong, Shi, Shuangping
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818804/
https://ncbi.nlm.nih.gov/pubmed/27088091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8356435
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