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NF-κB decoy oligodeoxynucleotide inhibits wear particle-induced inflammation in a murine calvarial model
Wear particles induce periprosthetic inflammation and osteolysis through activation of nuclear factor kappa B (NF-κB), which up-regulates the downstream target gene expression for proinflammatory cytokines in macrophages. It was hypothesized that direct suppression of NF-κB activity in the early pha...
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| Vydáno v: | J Biomed Mater Res A |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817851/ https://ncbi.nlm.nih.gov/pubmed/26123702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.35532 |
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