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Increased Valency of Conserved-mosaic Vaccines Enhances the Breadth and Depth of Epitope Recognition
The biggest roadblock in development of effective vaccines against human immunodeficiency virus type 1 (HIV-1) is the virus genetic diversity. For T-cell vaccine, this can be tackled by focusing the vaccine-elicited T-cells on the highly functionally conserved regions of HIV-1 proteins, mutations in...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817818/ https://ncbi.nlm.nih.gov/pubmed/26581160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.210 |
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