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Virus-mediated EpoR76E Therapy Slows Optic Nerve Axonopathy in Experimental Glaucoma

Glaucoma, a common cause of blindness, is currently treated by intraocular pressure (IOP)–lowering interventions. However, this approach is insufficient to completely prevent vision loss. Here, we evaluate an IOP-independent gene therapy strategy using a modified erythropoietin, EPO-R76E, which has...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Bond, Wesley S, Hines-Beard, Jessica, GoldenMerry, YPaul L, Davis, Mara, Farooque, Alma, Sappington, Rebecca M, Calkins, David J, Rex, Tonia S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817814/
https://ncbi.nlm.nih.gov/pubmed/26502777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.198
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