A time- and cost-effective strategy to sequence mammalian Y Chromosomes: an application to the de novo assembly of gorilla Y

The mammalian Y Chromosome sequence, critical for studying male fertility and dispersal, is enriched in repeats and palindromes, and thus, is the most difficult component of the genome to assemble. Previously, expensive and labor-intensive BAC-based techniques were used to sequence the Y for a handf...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Tomaszkiewicz, Marta, Rangavittal, Samarth, Cechova, Monika, Sanchez, Rebeca Campos, Fescemyer, Howard W., Harris, Robert, Ye, Danling, O'Brien, Patricia C.M., Chikhi, Rayan, Ryder, Oliver A., Ferguson-Smith, Malcolm A., Medvedev, Paul, Makova, Kateryna D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817776/
https://ncbi.nlm.nih.gov/pubmed/26934921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.199448.115
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