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Dosage regulation, and variation in gene expression and copy number of human Y chromosome ampliconic genes

The Y chromosome harbors nine multi-copy ampliconic gene families expressed exclusively in testis. The gene copies within each family are >99% identical to each other, which poses a major challenge in evaluating their copy number. Recent studies demonstrated high variation in Y ampliconic gene co...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Vegesna, Rahulsimham, Tomaszkiewicz, Marta, Medvedev, Paul, Makova, Kateryna D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772104/
https://ncbi.nlm.nih.gov/pubmed/31525193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008369
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