A time- and cost-effective strategy to sequence mammalian Y Chromosomes: an application to the de novo assembly of gorilla Y

The mammalian Y Chromosome sequence, critical for studying male fertility and dispersal, is enriched in repeats and palindromes, and thus, is the most difficult component of the genome to assemble. Previously, expensive and labor-intensive BAC-based techniques were used to sequence the Y for a handf...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Res
Egile Nagusiak: Tomaszkiewicz, Marta, Rangavittal, Samarth, Cechova, Monika, Sanchez, Rebeca Campos, Fescemyer, Howard W., Harris, Robert, Ye, Danling, O'Brien, Patricia C.M., Chikhi, Rayan, Ryder, Oliver A., Ferguson-Smith, Malcolm A., Medvedev, Paul, Makova, Kateryna D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2016
Gaiak:
Method
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817776/
https://ncbi.nlm.nih.gov/pubmed/26934921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.199448.115
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