Loading...
Genetic Modifiers of the p53 Pathway
The tumor suppressor gene TP53 is the most frequently mutated gene in human cancer; this gene is subject to inactivation by mutation or deletion in >50% of sporadic cancers. Genes that encode proteins that regulate p53 function, such as MDM2, MDM4, and CDKN2A (p14(ARF)) are also frequently altere...
Saved in:
| Published in: | Cold Spring Harb Perspect Med |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2016
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817744/ https://ncbi.nlm.nih.gov/pubmed/27037420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026302 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|