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The African-specific S47 polymorphism of p53 alters chemosensitivity
The TP53 protein is known to affect the sensitivity of tumor cells to cell death by DNA damaging agents. We recently reported that human and mouse cells containing an African-specific coding region variant of p53, Pro47Ser (hereafter S47), are impaired in the transactivation of a small subset of p53...
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| Publicado no: | Cell Cycle |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053554/ https://ncbi.nlm.nih.gov/pubmed/27484708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1215390 |
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