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Common genetic variants in the TP53 pathway and their impact on cancer
The TP53 gene is well known to be the most frequently mutated gene in human cancer. In addition to mutations, there are > 20 different coding region single-nucleotide polymorphisms (SNPs) in the TP53 gene, as well as SNPs in MDM2, the negative regulator of p53. Several of these SNPs are known to...
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| 出版年: | J Mol Cell Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6736421/ https://ncbi.nlm.nih.gov/pubmed/31152665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz052 |
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