Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium

Background: The observational relationship between obesity and periodontitis is widely known, yet causal evidence is lacking. Our objective was to investigate causal associations between periodontitis and body mass index (BMI). Methods: We performed Mendelian randomization analyses with BMI-associat...

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Bibliografski detalji
Izdano u:Int J Epidemiol
Glavni autori: Shungin, Dmitry, Cornelis, Marilyn C, Divaris, Kimon, Holtfreter, Birte, Shaffer, John R, Yu, Yau-Hua, Barros, Silvana P, Beck, James D, Biffar, Reiner, Boerwinkle, Eric A, Crout, Richard J., Ganna, Andrea, Hallmans, Goran, Hindy, George, Hu, Frank B, Kraft, Peter, McNeil, Daniel W, Melander, Olle, Moss, Kevin L, North, Kari E, Orho-Melander, Marju, Pedersen, Nancy L, Ridker, Paul M, Rimm, Eric B, Rose, Lynda M, Rukh, Gull, Teumer, Alexander, Weyant, Robert J, Chasman, Daniel I, Joshipura, Kaumudi, Kocher, Thomas, Magnusson, Patrik KE, Marazita, Mary L, Nilsson, Peter, Offenbacher, Steve, Davey Smith, George, Lundberg, Pernilla, Palmer, Tom M, Timpson, Nicholas J, Johansson, Ingegerd, Franks, Paul W
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Mendelian Randomization Causal Analysis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817600/
https://ncbi.nlm.nih.gov/pubmed/26050256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyv075
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