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Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium

Background: The observational relationship between obesity and periodontitis is widely known, yet causal evidence is lacking. Our objective was to investigate causal associations between periodontitis and body mass index (BMI). Methods: We performed Mendelian randomization analyses with BMI-associat...

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Detalhes bibliográficos
Publicado no:Int J Epidemiol
Main Authors: Shungin, Dmitry, Cornelis, Marilyn C, Divaris, Kimon, Holtfreter, Birte, Shaffer, John R, Yu, Yau-Hua, Barros, Silvana P, Beck, James D, Biffar, Reiner, Boerwinkle, Eric A, Crout, Richard J., Ganna, Andrea, Hallmans, Goran, Hindy, George, Hu, Frank B, Kraft, Peter, McNeil, Daniel W, Melander, Olle, Moss, Kevin L, North, Kari E, Orho-Melander, Marju, Pedersen, Nancy L, Ridker, Paul M, Rimm, Eric B, Rose, Lynda M, Rukh, Gull, Teumer, Alexander, Weyant, Robert J, Chasman, Daniel I, Joshipura, Kaumudi, Kocher, Thomas, Magnusson, Patrik KE, Marazita, Mary L, Nilsson, Peter, Offenbacher, Steve, Davey Smith, George, Lundberg, Pernilla, Palmer, Tom M, Timpson, Nicholas J, Johansson, Ingegerd, Franks, Paul W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817600/
https://ncbi.nlm.nih.gov/pubmed/26050256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyv075
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