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Reciprocal regulation of RORγt acetylation and function by p300 and HDAC1
T helper 17 (Th17) cells not only play critical roles in protecting against bacterial and fungal infections but are also involved in the pathogenesis of autoimmune diseases. The retinoic acid-related orphan receptor (RORγt) is a key transcription factor involved in Th17 cell differentiation through...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817527/ https://ncbi.nlm.nih.gov/pubmed/26549310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16355 |
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