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Enzyme Activities of the Ceramide Synthases CERS2–6 Are Regulated by Phosphorylation in the C-terminal Region

Ceramide and complex sphingolipids regulate important cellular functions including cell growth, apoptosis, and signaling. Dysregulation of sphingolipid metabolism leads to pathological consequences such as sphingolipidoses and insulin resistance. Ceramides in mammals vary greatly in their acyl-chain...

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Vydáno v:J Biol Chem
Hlavní autoři: Sassa, Takayuki, Hirayama, Taisuke, Kihara, Akio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817178/
https://ncbi.nlm.nih.gov/pubmed/26887952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695858
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