Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans

Cryptococcus neoformans is a leading cause of life-threatening fungal infection in immunocompromised patients. Inositol-phosphoryl ceramide synthase 1 (Ipc1) is a fungus-specific enzyme, encoded by the essential IPC1 gene, that catalyzes the formation of complex sphingolipids and may also regulate t...

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Hauptverfasser: Luberto, Chiara, Toffaletti, Dena L., Wills, Elizabeth A., Tucker, Stephanie C., Casadevall, Arturo, Perfect, John R., Hannun, Yusuf A., Del Poeta, Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2001
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC312614/
https://ncbi.nlm.nih.gov/pubmed/11157776
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