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Characterization of inositol phospho-sphingolipid-phospholipase C 1 (Isc1) in Cryptococcus neoformans reveals unique biochemical features

In this work, we biochemically characterized inositol phosphosphingolipid-phospholipase C (Isc1) from the pathogenic fungus Cryptococcus neoformans. Unlike Isc1 from other fungi and parasites which hydrolyze both fungal complex sphingolipids (IPC-PLC) and mammalian sphingomyelin (SM-PLC), C.neoforma...

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Detalhes bibliográficos
Main Authors: Henry, Jennifer, Guillotte, Aimee, Luberto, Chiara, Poeta, Maurizio Del
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045780/
https://ncbi.nlm.nih.gov/pubmed/21256847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.01.015
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