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Inositol Phosphosphingolipid Phospholipase C1 Regulates Plasma Membrane ATPase (Pma1) Stability in Cryptococcus neoformans
Cryptococcus neoformans is a facultative intracellular pathogen, which can replicate in the acidic environment inside phagolysosomes. Deletion of the enzyme inositol-phosphosphingolipid-phospholipase-C (Isc1) makes C. neoformans hypersensitive to acidic pH likely by inhibiting the function of the pr...
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Published in: | FEBS Lett |
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Main Authors: | , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
2014
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254033/ https://ncbi.nlm.nih.gov/pubmed/25240197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.09.005 |
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