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Inositol Phosphosphingolipid Phospholipase C1 Regulates Plasma Membrane ATPase (Pma1) Stability in Cryptococcus neoformans

Cryptococcus neoformans is a facultative intracellular pathogen, which can replicate in the acidic environment inside phagolysosomes. Deletion of the enzyme inositol-phosphosphingolipid-phospholipase-C (Isc1) makes C. neoformans hypersensitive to acidic pH likely by inhibiting the function of the pr...

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Bibliographic Details
Published in:FEBS Lett
Main Authors: Farnoud, Amir M., Mor, Visesato, Singh, Ashutosh, Del Poeta, Maurizio
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254033/
https://ncbi.nlm.nih.gov/pubmed/25240197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.09.005
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