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Methylation of glycosylated sphingolipid modulates membrane lipid topography and pathogenicity of Cryptococcus neoformans

In previous studies we showed that the replication of Cryptococcus neoformans in the lung environment is controlled by the glucosylceramide (GlcCer) synthase gene (GCS1), which synthesizes the membrane sphingolipid GlcCer from the C9-methyl ceramide. Here, we studied the effect of the mutation of th...

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Bibliografske podrobnosti
Main Authors: Singh, Arpita, Wang, Haitao, Silva, Liana C., Na, Chongzheng, Prieto, Manuel, Futerman, Anthony H., Luberto, Chiara, Del Poeta, Maurizio
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302964/
https://ncbi.nlm.nih.gov/pubmed/22151739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2011.01735.x
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