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Methylation of glycosylated sphingolipid modulates membrane lipid topography and pathogenicity of Cryptococcus neoformans

In previous studies we showed that the replication of Cryptococcus neoformans in the lung environment is controlled by the glucosylceramide (GlcCer) synthase gene (GCS1), which synthesizes the membrane sphingolipid GlcCer from the C9-methyl ceramide. Here, we studied the effect of the mutation of th...

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Detalhes bibliográficos
Main Authors: Singh, Arpita, Wang, Haitao, Silva, Liana C., Na, Chongzheng, Prieto, Manuel, Futerman, Anthony H., Luberto, Chiara, Del Poeta, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302964/
https://ncbi.nlm.nih.gov/pubmed/22151739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2011.01735.x
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